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Development and validation of a frailty index in the Longitudinal Aging Study Amsterdam

Frailty is a state of increased vulnerability to adverse outcomes. The frailty index (FI), defined by the deficit accumulation approach, is a sensitive instrument to measure levels of frailty, and therefore important for longitudinal studies of aging. The key characteristics of the LASA–FI are found to be in line with findings from previous FI studies in population-based samples of older people. The LASA–FI score was associated with mortality and may serve as an internal and external reference value.

Hoogendijk, E. O., Theou, O., Rockwood, K., Onwuteaka-Philipsen, B. D., Deeg, D. J. H., & Huisman, M. (2017). Development and validation of a frailty index in the Longitudinal Aging Study AmsterdamAging - Clinical and Experimental Research29(5), 927-933. 

DOI: https://doi.org/10.1007/s40520-016-0689-0

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