In the field of internationalization, Het Nieuwe Instituut has a number of formal genomes that are entrusted to the Agency and that, where possible, are linked to Het Nieuwe Instituut's substantive program. The exchange and development of knowledge, international cooperation and the expansion of networks are paramount.
Based on these tasks, Dutch designers are presented on various international stages, they are enabled to meet international curators, designers and researchers and become so-called cross-country overs that enable the exchange of knowledge. In addition, the Agency fulfills a coordinating role within the infrastructure of the Netherlands in the field of internationalization, which is reflected, for example, in the advisory function for designers who want to work abroad.
In the regional area, Het Nieuwe Instituut works together with local and social issues where a cultural interpretation can offer new approaches.