Viro-immunological, clinical and psychosocial facilities of disease severity and long-term outcomes of infection in SARSCov-2 - a prospective cohort study

De VIS studie is opgezet in samenwerking tussen de GGD Amsterdam en het Amsterdam UMC. Verder zijn een aantal expert-groeps betrokken om mee te denken met de data verzameling en analyses voor bepaalde onderwerpen, met name in de velden van: longgeneeskunde, psychologie/psychiatrie, en hematologie. De studie is een multi-centre studie. Er worden patienten geworven via locaties GGD Amsterdam, AMC, OLVG en VUmc. Deze patienten worden vervolgens opgevolgt bij de locaties GGD en AMC.

The overall aim of the proposed project is to establish a longitudinal cohort of adult patients who are infected with SARS-CoV-2, at different levels of disease severity, ranging from mild illness to severe requiring hospitalization and intensive care. These patients will be followed in a study for one year after initial diagnosis of infection.

This cohort will be used (1) to identify socio-demographic, clinical, virological and/ host factors predictive of disease progression, (2) to Investigate the induction of lasting protective SARS-CoV-2-specific antibody and SARS-CoV-2-specific T cell responses in relation to disease severity, clinical recovery or re-infection over time and (3) to gather insight into the clinical and socio-psychological sequelae of COVID-19. In addition, (4) a data- and biobank will be established for future in-depth pathophysiological, immunological, host-genetic and further clinical and epidemiologic studies.

Looptijd: 10-4-2020 - 31-12-2024

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Icon image: vis studie corona.jpg